Season
Episode
- Episode 1: Margot Robbie, Bobby Moynihan, Nathaniel Rateliff & the Night Sweats
- Episode 2: Kaley Cuoco, Mike Birbiglia, Ari Lennox
- Episode 3: Eli Manning, Chef José Andrés, Ana Fabrega, Michael Rowland
- Episode 4: Tyler Perry, Stephen A. Smith, Blood Orange
- Episode 5: Jon Hamm, Jurnee Smollett, The Smashing Pumpkins
- Episode 6: Nick Kroll, Jenna Bush Hager, Raymond Lee, Colum Tyrrell
- Episode 7: Kelly Ripa, Kid Cudi, Kid Cudi ft. Ty Dolla $ign
- Episode 8: Miles Teller, Idina Menzel, Babyface ft. Baby Tate
- Episode 9: Robert De Niro, Chloe Fineman, Arctic Monkeys
- Episode 10: Zac Efron, Debbie Harry, Lea Michele
- Episode 11: Naomi Watts, Jacob Batalon, Justin Thomas, Sam Hunt
- Episode 12: Ralph Macchio, Jennifer Beals, Lea Thompson, Modern English
- Episode 13: Reese Witherspoon, Kevin Nealon, Sabrina Wu
- Episode 14: Jack Harlow, Dwyane Wade, Quavo & Takeoff
- Episode 15: Mike Myers, Sutton Foster, Killer Mike
- Episode 16: Rachel Maddow, Noah Centineo, Fabien Frankel, Remi Wolf
- Episode 17: Pierce Brosnan, Charlie Puth, Kate del Castillo
- Episode 18: Dwayne Johnson, Camila Cabello, Ian Lara
- Episode 19: Trevor Noah, Antoni Porowski, Andrea Campos, Lil Baby
- Episode 20: Taylor Swift, Meghan Trainor
- Episode 21: Sigourney Weaver, Michaela Coel, Zedd & Maren Morris
- Episode 22: Jim Parsons, Rose Byrne, Isabel Hagen
- Episode 23: Millie Bobby Brown, Michael Imperioli, Tegan and Sara
- Episode 24: Lin-Manuel Miranda; Bobby Cannavale; JVKE
- Episode 25: Daniel Radcliffe; Winston Duke; Caroline Rhea
- Episode 26: Lupita Nyong'o; "Weird Al" Yankovic; Cameron Crowe; A Performance from Almost Famous
- Episode 27: George Lopez; Cole Hauser; LaTanya Richardson Jackson; Joey Bada$$ with Men I Trust
- Episode 28: Hasan Minhaj; Bashir Salahuddin and Diallo Riddle; Paramore
- Episode 29: Mariah Carey, Marcus Mumford ft. Monica Martin
- Episode 30: Ryan Reynolds; Jen Psaki; Smino
- Episode 31: Octavia Spencer; Matthias Schweighöfer; Kurt Braunohler
- Episode 32: Will Ferrell; Lindsay Lohan; The 1975
- Episode 33: Sylvester Stallone; Linda Cardellini; Louis Tomlinson
- Episode 34: Bruce Springsteen; Chloe Grace Moretz
- Episode 35: Seth Rogen; Jeremy Pope; Bruce Springsteen
- Episode 36: Anya Taylor-Joy; Glen Powell; Patti Smith; Bruce Springsteen
- Episode 37: Jessica Chastain; Martha Steweart; The Smile
- Episode 38: Samuel L. Jackson; Neal Brennan; Wizkid
- Episode 39: Tim Allen; Lacey Chabert; From "Bluey:, Dave McCormack & Melanie; Brent Faiyaz
- Episode 40: Michael Strahan; Chef Daniel Humm; Cole Swindell
- Episode 41: Jesse Eisenberg; Madelyn Cline; Jacques Pepin
- Episode 42: Jerry Seinfeld; Adam Devine; Bruce Springsteen
- Episode 43: Zoe Saldana; James Austin Johnson; A Performance from & Juliet
- Episode 44: Whoopi Goldberg; Sam Worthington; Gabe LaBelle; Manuel Turizo
- Episode 45: Dolly Parton; Claire Foy; DOMi & JD BECK; Mac DeMarco
- Episode 46: Adam Sandler; Greta Gerwig; Dane Cook; Babyface Ray; Keke Palmer
- Episode 47: Kevin Bacon; Theo James; Jay Jurden
- Episode 48: Selena Gomez; Sebastian Maniscalco; beabadoobee
- Episode 49: Emma Thompson; Guillermo del Toro; Ashley McBryde; John Osborne
- Episode 50: Michelle Pfeiffer; Lil Rel Howery; Clive Davis; Goose
- Episode 51: Steve Martin; Martin Short; H.E.R.; Adam Blackstone; Mary Mary; Inayah; The BBE Big Band
- Episode 52: Miley Cyrus, Jesse Williams; Mary Mack
- Episode 53: Kate Hudson, Morris Chestnut
- Episode 54: Stanley Tucci, Michael Che; Sean Patton; Muni Long
- Episode 55: Salma Hayek, Wiz Khalifa
- Episode 56: Regina Hall, F. Murray Abraham, Edvin Ryding; Omar Rudberg, Andrea Matteo & Virginia Bocelli
- Episode 57: James Corden; Jenna Ortega; Mike Finney
- Episode 58: Ana de Armas; Luke Grimes; Protoje
- Episode 59: Winston Duke; Darren Aronofsky; Emma Myers; Idles
- Episode 60: Savannah Guthrie & Hoda Kotb; Colin Quinn; Madison Cunningham
- Episode 61: Allison Williams; Jessie Reyez
- Episode 62: Al Pacino and Logan Lerman, Rupert Grint; Dry Cleaning
- Episode 63: Leslie Jones, Giancarlo Esposito; Alvvays
- Episode 64: Finn Wolfhard; Meghann Fahy; Drew Scott; Jonathan Scott; Myke Towers
- Episode 65: Chelsea Handler; Matthew Macfadyen; Ralph Barbosa
- Episode 66: Lea Michele; Sadie Sink; Dayglow
- Episode 67: Aubrey Plaza; Jalyn Hall; Sudan Archives
- Episode 68: Katie Holmes; Danielle Deadwyler; Anuel AA
- Episode 69: Yara Shahidi; John Leguizamo; SG Lewis
- Episode 70: John Oliver; Sam Smith; Fahim Anwar
- Episode 71: Colin Jost; Kenya Barris; Tobe Nwigwe
- Episode 72: Aaron Judge; Josh Duhamel; Freddie Gibbs ft. Anderson .Paak
- Episode 73: Natasha Lyonne; Nate Bargatze; Brianne Howey & Antonia Gentry; Stephen Sanchez
- Episode 74: Keke Palmer; Jeff Gordon; Lauren London; HARDY ft. Lainey Wilson
- Episode 75: Michael B. Jordon; Hugh Dancy; Maneskin; Maneskin ft. Tom Morello
- Episode 76: Claire Danes; Roman Reigns; Cathy Ladman
- Episode 77: Austin Butler; Rob Gronkowski; Tyler Hubbard
- Episode 78: Dave Bautista; Sarah Michelle Gellar; Bryan Adams
- Episode 79: Derek Jeter; Rita Ora
- Episode 80: Pedro Pascal; Kathryn Newton; Armani White
- Episode 81: Kit Harington; Tyler James Williams; Paul Shaffer and the World's Most Dangerous Band
- Episode 82: Ashton Kutcher; Alison Brie; Dermot Kennedy
- Episode 83: Christoph Waltz; Tig Notaro; Fitz and the Tantrums
- Episode 84: Queen Latifah; M. Night Shyamalan; Orlando Leyba
- Episode 85: Matthew McConaughey; Evangeline Lilly; Jorma Taccone; Lang Lang
- Episode 86: Paul Rudd; Marc Maron; Kelela
- Episode 87: Elizabeth Banks; Kelsey Grammer
- Episode 88: Chip Gaines; Joanna Gaines; Rhett and Link; Amanda Shires; Jason Isbell
- Episode 89: Liam Neeson; Jack Whitehall; Nate Smith
- Episode 90: James Spader; Jay Hernandez; Travis Kelce; Samara Joy
- Episode 91: Adam Scott; Elizabeth Debicki; Nathan Macintosh
- Episode 92: Gigi Hadid; Chase Stokes; Micky Dolenz; Dierks Bentley
- Episode 93: Willem Dafoe; Marlon Wayans; Macklemore; Kelsey Cook
- Episode 94: Ice T; Stephanie Hsu; Adam Lambert
- Episode 95: Brendan Fraser; Tan France; Lizzy McAlpine
- Episode 96: Tessa Thompson; Andy Cohen; The National
- Episode 97: Maude Apatow; Chance the Rapper
- Episode 98: Adam Driver; Ana Gasteyer; Macklemore; Morray
- Episode 99: Kerry Washington; Jenna Lyons; St. Vincent; The Roots
- Episode 100: Jenna Ortega; Hannah Waddingham; TWICE
- Episode 101: Lucy Liu; Damson Idris; Bizarrap; Shakira
- Episode 102: Bob Odenkirk; Paris Hilton; Collin Morikawa; Asake
- Episode 103: Bryan Cranston; Penn Badgley; Maya Hawke
- Episode 104: Keira Knightley; Zachary Levi; Rina Sawayama; Nore Davis
- Episode 105: Keanu Reeves; Melanie Lynskey; De La Soul & The Roots
- Episode 106: Kenan Thompson; Kel Mitchell; Padma Lakshmi
- Episode 107: Florence Pugh; Andrew Lloyd Webber; Talib Kweli; Madlib
- Episode 108: Jennifer Aniston; Sarah Snook; Preacher Lawson
- Episode 109: Brian Cox; Gaten Matarazzo; Mikaela Shiffrin; Caroline Polachek
- Episode 110: Kiefer Sutherland; Jimin; Fall Out Boy
- Episode 111: Kieran Culkin; Method Man; Jimin
- Episode 112: Nathan Lane; Dove Cameron; Lil Uzi Vert
- Episode 113: Adam Sandler; Nicholas Hoult; Penn & Teller
- Episode 114: Kevin Bacon; Jay Pharoah; Coco Jones
- Episode 115: Edward Norton; Ego Nwodim; Parker McCollum
- Episode 116: Chris Pratt; Elizabeth Vargas; Maisie Peters
- Episode 117: Michelle Williams; John Stamos; Mo Willems; CHVRCHES
- Episode 118: Keegan-Michael Key, Richard Branson, Blondshell
- Episode 119: Matt Damon, Cecily Strong, Rema
- Episode 120: Molly Shannon, Ramon Rodriguez, Sophie Buddle
- Episode 121: Jonas Brothers, Chloe Bailey, Foodie Magician
- Episode 122: Chris Evans, Andrew Lloyd Webber, Toosii
- Episode 123: Ana de Armas, Jesse Plemons, Mike Vecchione
- Episode 124: Michelle Obama, Kelvin Harrison Jr., Sampa The Great, Angélique Kidjo
- Episode 125: Ray Romano; Zoe Lister-Jones; Flo
- Episode 126: Sienna Miller; Nikolaj Coster-Waldau; Ryan Hamilton
- Episode 127: Kate Beckinsale; Rainn Wilson; Remeo Santos
- Episode 128: Jude Law; Joshua Jackson
- Episode 129: Michael Strahan; Judy Blume; Black Thought, El Michels Affair and KIRBY
- Episode 130: Drew Barrymore; Lizzy Caplan; Young Mazino: The National
- Episode 131: Pete Davidson; Questlove; S.A. Cosby; Peso Pluma
- Episode 132: Rosie O'Donnell; SUGA
The Tonight Show Starring Jimmy Fallon Season 10 Derek Jeter; Rita Ora
After Jay Leno's second retirement from the program, Jimmy Fallon stepped in as his permanent replacement. After 42 years in Los Angeles the program was brought back to New York.
